Pre-course reading suggestions

If you have time before coming to the course to read the articles below, and to make notes of questions you have while reading them, then we recommend you do this. Learning research shows that you are likely to learn more if you begin a course having already spent time reading and thinking about the issues and topics covered in the course.


Intrinsically unstructured proteins and their functions.
Dyson HJ, Wright PE.
Nat Rev Mol Cell Biol. 2005 Mar;6(3):197-208.
PMID: 15738986 http://www.ncbi.nlm.nih.gov/pubmed/15738986
http://www.nature.com/nrm/journal/v6/n3/full/nrm1589.html


Protein interaction networks from yeast to human.
Bork P, Jensen LJ, von Mering C, Ramani AK, Lee I, Marcotte EM
Curr Opin Struct Biol. 2004 Jun;14(3):292-9
PMID: 15193308
http://www.ncbi.nlm.nih.gov/pubmed/15193308
http://www.sciencedirect.com/science/article/pii/S0959440X04000776


Short linear motifs: ubiquitous and functionally diverse protein interaction modules directing cell regulation.
Van Roey K, Uyar B, Weatheritt RJ, Dinkel H, Seiler M, Budd A, Gibson TJ, Davey NE
Chem Rev. 2014 Jul 9;114(13):6733-78. doi: 10.1021/cr400585q
PMID: 24926813
http://www.ncbi.nlm.nih.gov/pubmed/24926813
http://pubs.acs.org/doi/full/10.1021/cr400585q


An introduction to sequence similarity (“homology”) searching.
Pearson WR.
Curr Protoc Bioinformatics. 2013 Jun;Chapter 3:Unit3.1. doi: 10.1002/0471250953.bi0301s42.
PMID: 23749753
http://www.ncbi.nlm.nih.gov/pubmed/23749753